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Oat flour with avenanthramides

Introduction

Oat flour, a natural ingredient, is gaining popularity in the cosmetics industry. One of the outstanding components of oat flour is avenanthramides, which are known for their anti-inflammatory and skin-soothing properties. In this article, we will explore the benefits of oat flour with avenanthramides, the scientific evidence of its efficacy and its application in cosmetic products.

 

What are avenanthramides?

Avenanthramides are phenolic compounds found in oats (Avena sativa). They are known for their strong antioxidant and anti-inflammatory properties. These compounds are valued in cosmetics and dermatology because they can relieve skin irritation, strengthen the skin barrier and improve the appearance of the skin.

 

Scientific studies on the efficacy of oat flour with avenanthramides

Several studies have investigated the efficacy of oat flour with avenanthramides in the treatment of skin problems. Here are some important results:

 

  1. Anti-inflammatory effect: One study showed that avenanthramides can significantly inhibit the release of interleukin-8 (IL-8), a pro-inflammatory cytokine. This suggests that avenanthramides have anti-inflammatory properties that may be useful in the treatment of inflammatory skin conditions such as atopic dermatitis

Results in detail:

o    IL-8 release: A significant reduction in IL-8 release was observed, indicating a strong anti-inflammatory effect.

o    NF-κB inhibition: Avenanthramides inhibited the activation of the NF-κB signalling pathway, which plays a central role in inflammatory processes.

 

  1. Wound healing: A wound healing study showed that avenanthramides improve the rate of wound healing and increase the quality of the healed tissue. The study showed that avenanthramides promote a similar extracellular matrix structure to untreated skin tissue and reduce the number of inflammatory cells in the healed tissue.

Results in detail:

o    Wound closure: A significant acceleration of wound healing with 1% avenanthramide treatment compared to the control group.

o    Collagen architecture: The treated wounds showed a shorter and more randomly arranged collagen fibre structure, indicating a regenerative tissue architecture.

o    Inflammatory cells: Reduced recruitment of inflammatory cells compared to the control group.

 

  1. Skin soothing and reduction of itching: A clinical study with an avenanthramide-containing moisturising cream showed that the application of the cream in patients with atopic dermatitis and eczema led to a significant improvement in skin dryness, cracking, scaling and itching within four weeks.

Results in detail:

o    Skin dryness: An improvement of over 50% within the first week of application.

o    Itch reduction: A significant reduction in itching was observed in patients, which significantly improved the quality of life of those affected.

 

Use of oat flour with avenanthramides in cosmetics

Oat flour with avenanthramides is a valuable ingredient in various cosmetic products. The benefits include:

  • Skin soothing: Oat flour with avenanthramides helps to soothe skin irritation and redness, making it ideal for sensitive skin types.
  • Moisturising: The moisturising properties help to keep the skin supple and hydrated.
  • Protection of the skin barrier: Oat flour strengthens the skin barrier and protects against harmful environmental influences.
  • Antioxidant properties: The antioxidant properties of avenanthramides protect the skin from free radicals and premature aging.

The importance of the INCI declaration

For cosmetic products, it is important that avenanthramides are correctly declared in the International Nomenclature of Cosmetic Ingredients (INCI). Only if avenanthramides are listed as such is it a standardised extract. If this declaration is missing, the consumer cannot be sure that the product actually contains the active ingredients.

 

Conclusion

Oat flour with avenanthramides offers numerous benefits for skin care and is a valuable ingredient in cosmetic products. Its anti-inflammatory, antioxidant and skin-soothing properties make it an excellent choice for the care of sensitive and problematic skin. The correct INCI declaration of avenanthramides ensures that consumers can fully benefit from the advantages of this effective extract. The use of oat flour with avenanthramides in the cosmetics industry will certainly continue to increase as more and more scientific evidence supports its effectiveness. Please feel free to contact us if you would like to take your products for this target group to the next level.

We only use Cosactive Oat 250, which is standardised with at least 250 mg avenanthramides. 

www.cosactive.de/

 

Literature:

 

Phenolic amides (avenanthramides) in oats – an update review.

Xie X, Lin M, Xiao G, Liu H, Wang F, Liu D, Ma L, Wang Q, Li Z.Bioengineered. 2024 Dec;15(1):2305029.

Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases.

Perrelli A, Goitre L, Salzano AM, Moglia A, Scaloni A, Retta SF.Oxid Med Cell Longev. 2018 Aug 23;2018:6015351

Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health.

Kim IS, Hwang CW, Yang WS, Kim CH.Antioxidants (Basel). 2021 Sep 13;10(9):1454

Oat (Avena sativa) Extract against Oxidative Stress-Induced Apoptosis in Human Keratinocytes.

Song S, Lee YM, Lee YY, Yeum KJ.Molecules. 2021 Sep 13;26(18):5564.

Cytoprotective effects of Avenathramide C against oxidative and inflammatory stress in normal human dermal fibroblasts.

Wang C, Eskiw CH.Sci Rep. 2019 Feb 27;9(1):2932