Active ingredient enhancement
Innovation to improve efficacy by improving the water solubility of active ingredients
Our partner Asoltech is a company that specializes in the research and development of highly effective ingredients used in food, dietary supplements, medical devices and nutricosmetic products.
A key aspect of their technology is the enhancement of efficacy by improving the water solubility of active ingredients. In the following, we present Asoltech’s active ingredient enhancement technologies and explain the existing active ingredients and their benefits in cosmetic formulations.
Active ingredient enhancement technology
EGIPRO – Ecosustainable Grinding Industrial Process
Asoltech uses a proprietary, environmentally friendly technology called EGIPRO (Ecosustainable Grinding Industrial Process). This method enables the production of customized ingredients with improved physico-chemical properties, such as increased water solubility, stability and taste. The active ingredient enhancement technology enables a more efficient and effective use of the ingredients in different formulations.
Goals and results
The main objective of EGIPRO technology is to improve efficacy by optimizing the physico-chemical properties of the active ingredients. The results include tailor-made ingredients that meet specific requirements, improved bioavailability and increased efficacy. These improvements lead to optimized absorption and utilization of the active ingredients in cosmetic products.
Existing active ingredients and their benefits
ASOLQUTEN
Asolquten contains 25 % coenzyme Q10 (CoQ10) and offers significantly improved water solubility. In an in vitro study, it was shown that Asolquten has a significantly higher ROS (Reactive Oxygen Species) scavenging activity compared to pure CoQ10. This leads to an improved cellular protective effect. The active ingredient enhancement makes Asolqutene an ideal option for anti-aging products and antioxidant formulations.
MELASOL
Melasol contains 15 % melatonin and shows improved bioavailability and absorption. By improving the efficacy, the solubility and release of melatonin is optimized, making Melasol an effective ingredient for skin regeneration and oxidative stress protection products.
NACESOL
Nacesol combines N-acetylcysteine (NAC) with resveratrol and has 15 times more antioxidant activity than pure NAC. This active ingredient enhancement makes Nacesol a potent ingredient for products that aim to protect the skin from environmental damage and oxidative stress.
PROPOSOL
Proposol contains 10 % propolis extract and shows an up to 50-fold improvement in the solubility of the active components. This makes it an effective ingredient for topical applications for inflammations and infections, especially in oral care.
CURCUMIN AST
Curcumin AST contains 20 % curcumin and shows improved bioavailability and absorption. This improved efficacy makes Curcumin AST an ideal ingredient for products that require anti-inflammatory and antioxidant properties.
HYDRORUTIN
Hydrorutin contains 20 % rutin and offers a 25-fold improvement in solubility. It is an effective ingredient for cosmetic products used to treat couperose and sensitive skin.
Application in cosmetic formulations
The active ingredients developed so far offer numerous advantages for cosmetic formulations:
- Increased bioavailability: The active ingredient enhancement allows the ingredients to be better absorbed by the skin, resulting in increased effectiveness.
- Improved stability: The optimized physico-chemical properties ensure greater stability and longer shelf life of the ingredients.
- Wide range of applications: The increased water solubility allows the active ingredients to be used in a wider range of cosmetic products, including creams, serums and gels.
- Effective anti-ageing products: The ingredients ASOLQUTEN and CURCUMIN AST have powerful antioxidant properties that can help reduce wrinkles and protect against environmental damage.
- Soothing and protective properties: Products with HYDRORUTIN and PROPOSOL can soothe skin irritations and provide anti-inflammatory effects.
Conclusion
Asoltech’s innovative technologies to improve efficacy by enhancing the water solubility of active ingredients offer significant benefits to the cosmetic industry. The improved ingredients are not only more effective, but also more stable and versatile. With these advances, Asoltech is setting new standards in the development of highly effective cosmetic products that protect, care for and regenerate the skin.
The consistent application of active ingredient enhancement technology ensures that Asoltech ingredients meet the high demands of modern cosmetic formulations and are also produced in an environmentally friendly and sustainable manner. We would be happy to develop the appropriate active-enhancing substances for your products.
Literature:
Patent for this technology
https://patentimages.storage.googleapis.com/aa/8f/b6/a50cace7986dbe/EP3220893B1.pdf