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Matrixyl-3000

Introduction

Matrixyl-3000 is a groundbreaking anti-ageing active ingredient that has been specially developed to combat the visible signs of skin ageing. In this article, we will introduce the active ingredients it contains and their physical and chemical properties, explain the efficacy data and explain how wrinkles develop. The focus is on the specific variants MATRIXYL-3000 OS and MATRIXYL-3000 Glyx.

 

What is Matrixyl-3000?

Matrixyl-3000 is a combination of two palmitoylated matrikine peptides: Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. These peptides act as messengers that regulate the activity of skin cells by interacting with specific receptors. In doing so, they activate genes that are involved in the renewal of the extracellular matrix and cell proliferation, processes that weaken with age.

 

Physical-chemical properties of Matrixyl-3000

Matrixyl-3000 consists of the following main ingredients:

Palmitoyl Tripeptide-1: A peptide that stimulates collagen production.

Palmitoyl Tetrapeptide-7: A peptide with anti-inflammatory properties that promotes skin regeneration.

 

Matrixyl-3000 OS:

– INCI: C12-15 Alkyl Benzoate, Sorbitan Laurate, C18-36 Acid Glycol Ester, C18-36 Acid Triglyceride, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

– Form: oil soluble

Matrixyl-3000 Glyx:

– INCI: Glycerin, Aqua (water), Xanthan, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

– Form: water-soluble

 

Both variants are suitable for formulation in various cosmetic products and offer flexibility in product development.

 

The formation of wrinkles

Wrinkles are caused by a number of factors:

Ageing: As we age, the production of collagen and elastin in the skin slows down, causing the skin to lose firmness and elasticity.

UV radiation: Sunlight accelerates the breakdown of collagen and elastin, leading to premature skin ageing.

Environmental influences: factors such as pollution and smoking also contribute to the formation of wrinkles by generating free radicals that damage skin cells.

 

Data on the effectiveness of Matrixyl-3000

The effectiveness of the anti-ageing active ingredient has been tested in various clinical studies. Here are some noteworthy results:

Reduction of wrinkles: One study showed that daily application of a cream containing 3% Matrixyl-3000 over a period of two months reduced the area of the deepest wrinkles by up to 39.4% and the wrinkle density by 32.9%. The average wrinkle depth was reduced by 19.9%.

Improvement of skin density and thickness: When applied to the inner and outer sides of the forearms, a significant improvement in skin density and thickness was observed, resulting in a rejuvenation of the skin by 3.8 to 5.5 years.

– Stimulation of collagen production: Matrixyl-3000 stimulated the synthesis of collagen I, fibronectin and hyaluronic acid, resulting in a visible improvement in skin structure and firmness.

 

Conclusion

Matrixyl-3000 is a highly effective anti-aging active ingredient that impresses with its unique properties and extensive clinical evidence. The peptides palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 contained in it promote skin regeneration and effectively reduce the signs of skin aging. With the variants MATRIXYL-3000 OS and MATRIXYL-3000 Glyx, this active ingredient offers flexible solutions for different cosmetic formulations. Use the power of this ingredient to offer your customers visible and long-lasting results. Contact us for innovative products and textures.

 

Literature:

Usage of Synthetic Peptides in Cosmetics for Sensitive Skin.

Resende DISP, Ferreira MS, Sousa-Lobo JM, Sousa E, Almeida IF.Pharmaceuticals (Basel). 2021 Jul 21;14(8):702

A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos analysis and frequently repeated auto-perception.

Lintner K, Gerstein F, Solish N.J Cosmet Dermatol. 2020 Dec;19(12):3262-3269